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Scientists at the University of Cambridge in collaboration with the University of Glasgow and other worldwide institutions have discovered that inflammation is amplified by the very cells which are supposed to help fight infection in a host of inflammatory diseases including Crohn's Disease and Ulcerative Colitis, the two main forms of Inflammatory Bowel Disease.
Cell research discovery opens doors for potential new treatments
The researchers found that these macrophage cells, the “infection fighters”, sometimes activate mitochondria “cell batteries”, the “energy producers” which in turn produce toxins which lead to further inflammation.
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This research offers real hope for people living with Inflammatory Bowel Disease. A new target has been discovered in the inflammation pathway for potential new treatments. Further research will be needed to take this discovery to the next stage but it opens new doors and offers new opportunities.
Crohn's & Colitis UK are currently funding research related to faulty mitochondria “cell batteries” at the University of Edinburgh:
Crohn's & Colitis UK are committed to funding research into all areas of Inflammatory Bowel Disease. Find out more information about the research projects we are currently funding.
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Last updated: 22/07/2026
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