Crohn's & Colitis UK, has granted just under £500,000 in funding for their Research Awards for 2016. Six innovative projects have been selected for funding to investigate possible causes which could eventually lead to new treatments and ultimately a cure.
£478,000 awarded to innovative research in the hope of new IBD treatments
For over 30 years, Crohn’s & Colitis UK has been at the forefront of ground breaking research on Crohn's Disease and Ulcerative Colitis, the two main forms of Inflammatory Bowel Disease (IBD). In 2016, the charity has been able to grant vital funds to research projects that offer hope to people living with IBD, value for money and originality.
The following research projects have had funding committed by Crohn’s & Colitis UK for 2016:
Kings College London will receive £88,668 to look at pain management with the aim to develop a new intervention for IBD abdominal pain, and compare it with existing NHS pain management programs.
If we show that interventions make a difference to IBD pain we will have a strong argument for the NHS to provide this service to people with IBD and we will be able to train IBD nurses to deliver help for pain as part of their role.
The University of Edinburgh will receive £8,000 to investigate the ‘faulty batteries’ inside cells, studying the role of damaged mitochondria in causing Inflammatory Bowel Disease.
Our current study seeks to investigate the importance of damaged mitochondrial ‘danger signals’ in driving the inflammatory response in IBD.
The University of Liverpool will receive £49,579 to develop a blood test for Ulcerative Colitis patients to predict how well biological drugs will work, helping clinicians make an informed choice about the best biological drug treatment.
Identification of accurate predictors of response prior to commencing therapy will minimize time spent with active disease and enable the clinician to make an informed decision to commence the treatment to which the patient is most likely to respond.
Leeds University will receive £116,272 to investigate bowel cancer in IBD. The study will look at the number of people with IBD who develop bowel cancer, the people who are at most risk, and what medications may prevent it.
Identifying optimum surveillance intervals, high risk patients and potential chemopreventive agents could help reduce the burden of invasive testing on patients and healthcare organization authorities while still providing maximum clinical benefit to patients.
The University of Edinburgh will receive £100,089 to look at the role of microRNA in Inflammatory Bowel Disease which will investigate the possibility of a new blood test to diagnose IBD early and predict how the disease may progress.
We hope to develop a blood-based biomarker to help diagnose IBD and predict which patients may go on to require potent medical treatments or surgery.
The University of Cambridge will receive £115,701 to research what switches genes on and off. The study will look at epigenetics in peadiatric Inflammatory Bowel Disease.
Providing robust evidence that epigenetic mechanisms are critical in the development of IBD would open up the real possibility of a whole new approach to treatment.
We have come a long way in our understanding of Inflammatory Bowel Diseases, but there is still so much we do not know about these unpredictable, life-long and potentially life-threatening conditions. These investments into research are critical if we want to improve lives now and ultimately find a cure. We are delighted that we have been able to fund so many innovative projects that we hope will prove ground-breaking in learning more about possible causes and finding new treatments for over 300,000 people in the UK who currently have IBD.
Applications for 2017 research grants are now open
The charity grants three kinds of awards: for medical research, for research into the social and psychological impacts of the condition, and for research into improving health services for people with IBD.
Funding for any one project is normally subject to a maximum of £120,000 over a period of up to three years. Applications for funding of pilot studies are also encouraged.
The closing date for applications is Monday 26 September 2016 at 4:00 pm.
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