SEARCH
NICE has opened a public consultation on its interim guidance on vedolizumab for moderately to severely active Ulcerative Colitis. Its preliminary decision is that vedolizumab is recommended as a treatment option for moderately to severely active Ulcerative Colitis. However, it is not recommended for those who have previously been treated with anti-TNF drugs.
We welcome positive recommendation for vedolizumab for UC but say it's missing those most in need.
We very much welcome this early indication that there will an additional and promising new treatment option available for people with Ulcerative Colitis, for whom current options are very limited. This is an important and positive development. However, we are very disappointed that this may not be available to those who have not had a response to, or have lost response to treatment with a TNF-alpha inhibitor, such as infliximab or adalimumab.
For people in this situation, there may be no other options except surgery, with all the implications that this can bring.
“”
I am extremely disappointed that this drug will not be available for people like me for whom anti-TNFs have not worked. I have been in remission for six years, after many years of trying lots of other treatments with no success and a tremendous toll on my body. My life has changed completely and I dread going back to the life I had to endure before.
We urge NICE to reconsider extending this treatment option to include those who are most in need.
We will be highlighting the consultation on our website www.crohnsandcolitis.org.uk and encouraging members and supporters to register their views directly with NICE before the consultation deadline on 17th December.
For more information or comment please contact media@crohnsandcolitis.org.uk or call the Media Office at 01428 607627.
Read our latest news
Catch up on the latest news from Crohn’s & Colitis UK
Page
saved
This page has been saved in your personal space. Go to “My Page” to view all saved pages.
Helpline Service
Temporary closure - 10/06/2026
Our Helpline will be closed from Wednesday 10 June and will reopen at 10am on Monday 15 June.
We may be closed but we have lots of information here on our website.
If you need urgent medical advice you can call NHS 111 or in Northern Ireland phone your local Phone First. In an emergency call 999 or go to your nearest A&E.
If you need emotional support the Samaritans are available 24 hours a day, 7 days a week on 116 123.
We know it can be difficult to live with, or support someone living with Crohn’s or Colitis. But we’re with you. We can give you the right information and support at the right time.
We’re here for everyone.
How Can We Help?
- We can help you understand Crohn’s and Colitis
- Listen and talk about living with IBD
- Help you connect with others in the Crohn’s and Colitis community
- Give you contact details of specialist organisations
- We can support you to live well with Crohn’s or Colitis and provide up-to-date, evidence-based information
Please be aware we’re not medically or legally trained. We cannot provide detailed financial or benefits advice or specialist emotional support.
Please contact us via telephone, email or LiveChat - 10am to 3pm, Monday to Friday (except English bank holidays).
If you need specific medical advice about your condition, your GP or IBD team will be best placed to help.
Stay in the loop
Together, we’re making the greatest difference. Sign up to hear about the amazing things we’re achieving together.
© Crohn's & Colitis UK