Vedolizumab

Last updated: May 2025

Last full review: May 2023

Next review date: May 2026

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This information is for people with Crohn’s or Colitis who are on vedolizumab (Entyvio) treatment or who are thinking about starting it. This information can help you to decide if this treatment is right for you. It looks at:

  • How vedolizumab works
  • What you can expect from vedolizumab
  • How to take vedolizumab
  • Possible side effects
  • Stopping or changing treatment

This information might use words you have not heard before. Our page on medical words can help provide an explanation.

This information is about vedolizumab in general. It should not replace advice from your IBD team.

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  • Key facts about vedolizumab
  • Other names for vedolizumab
  • Deciding which medicine to take
  • How vedolizumab works
  • Why you might be offered vedolizumab
  • How quickly can vedolizumab work?
  • How well does vedolizumab work in Crohn’s and Colitis?
  • How long will you take vedolizumab for?
  • How to take vedolizumab
  • Side effects
  • Checks before starting vedolizumab
  • Ongoing checks
  • Taking vedolizumab with other medicines for Crohn’s or Colitis
  • Vaccinations
  • Taking other medicines
  • Drinking alcohol
  • Pregnancy and fertility
  • Breastfeeding
  • About this information

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We know it can be difficult to live with, or support someone living with these conditions. But you’re not alone. We provide up-to-date, evidence-based information and can support you to live well with Crohn’s or Colitis.

Our helpline team can help by:

  • Providing information about Crohn’s and Colitis.

  • Listening and talking through your situation.

  • Helping you to find support from others in the Crohn’s and Colitis community.

  • Providing details of other specialist organisations.

Please be aware we’re not medically or legally trained. We cannot provide detailed financial or benefits advice or specialist emotional support.

Please contact us via telephone, email or LiveChat - 9am to 5pm, Monday to Friday (except English bank holidays).

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If you need specific medical advice about your condition, your GP or IBD team will be best placed to help.

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