Treatment for Crohn’s Disease and Ulcerative Colitis depends on how severe the symptoms are, and how much of the gut is affected.
Treatments
There are many different treatments available to help you live well with your Crohn’s or Colitis. Together with your IBD team, you can decide what treatment is right for you.
At first, medicines aim to reduce inflammation in the gut to bring about remission. Remission is when you feel better and your Crohn's or Colitis symptoms aren't bothering you. Once the condition is under control, your doctor will usually continue to prescribe drugs to maintain remission and prevent relapse (feeling unwell again) – this is called maintenance treatment.
Medicines to treat Crohn's and Colitis
Immunosuppressant medicines
These medicines control the immune system to stop it attacking the gut:
- Adalimumab
- Azathioprine and Mercaptopurine
- Biologic Drugs
- Etrasimod
- Filgotinib
- Golimumab
- Guselkumab
- Infliximab
- Methotrexate
- Mirikizumab
- Ozanimod
- Risankizumab
- Steroids
- Tofacitinib
- Upadacitinib
- Ustekinumab
- Vedolizumab
Other medicines
Surgery
Sometimes people with Crohn's or Colitis require surgery. A range of surgeries can be recommended and these guides looks at what they are and when they are necessary, weighing up the pros and cons in the process:
Other forms of treatment
Browse all our information for details about other forms of treatment for Crohn’s and Colitis, including dietary therapy, counselling and controlling fatigue.
About Crohn's and Colitis
Support for you
Helpline Service
Last updated: 22/07/2026
Our Helpline team can't take calls, chats or ring you back for the rest of the summer. But you can still reach us by email.
If you need to contact the team, please email helpline@crohnsandcolitis.org.uk and we'll answer you as soon as possible.
Thanks for bearing with us.
How Can We Help?
- We can help you understand Crohn’s and Colitis
- Listen and talk about living with IBD
- Help you connect with others in the Crohn’s and Colitis community
- Give you contact details of specialist organisations
- We can support you to live well with Crohn’s or Colitis and provide up-to-date, evidence-based information
Please be aware we’re not medically or legally trained. We cannot provide detailed financial or benefits advice or specialist emotional support.
If you need specific medical advice about your condition, your GP or IBD team will be best placed to help.